Investigating and amplifying the theme of the 2023 Global Healthspan Summit, Together We Thrive, the Global Healthspan Summit sits down with a special guest speaker.

The NIH and WHO have declared Metabolic Syndrome to be an epidemic. Many researchers now believe that metabolic dysfunction is strongly affiliated with Alzheimer’s, going as far as calling it ‘type 3 diabetes.’ How might promoting metabolic health be a preventative measure for Alzheimer’s and prolong a healthy lifespan?
The fight against Alzheimer’s disease demands collective action, leadership and unwavering commitment. As investments, donations and organizations converge, they catalyze the acceleration of groundbreaking studies, paving the way for innovative drug that hold the promise to prevent and treat this formidable affliction. How can leaders and stakeholders further galvanize global efforts to not just mitigate the impact of Alzheimer’s but seek its ultimate cure.

Spotlight on the catalytic impact Hevolution investments promise to have in driving scientific advancement. How does this funding support in driving science forward? 

With the recent advancements in Al, wearables and spatial computing (AR, VR, MxR), the promise of advancing Healthspan by leveraging technology is becoming more of a reality, but how do we achieve Healthspan at scale?  Meet people where they are.   We interact with technology in every aspect of our lives.   By analyzing the intricacies of the human-machine interface, we can derive insights to advance Healthspan and prioritize human-centric approaches to AI. Utilizing the paradigm of video games as an illustration of human-machine interfaces, we explore how 3.2+ billion people playing video games have the potential to empower global health initiatives. Additionally, we examine the benefits of incorporating new approaches of enhancing Healthspan, from telemetry to treatment, via video games and wearables. 

Gain first-hand insight into the transformative impact digital twins will soon have on longevity, environment - and the economy. In this exclusive conversation with NEOM, we delve into the new and integrated health, wealth and biotech ecosystem that promises to go far beyond and above traditional medical care. Centred entirely on our individual profiles - digital twins have a key role to play in this new world of treatment and inclusive care. 

How do we realize the manifold opportunities of healthy longevity as we enter the era of long lives? For children born since 2000, a life expectancy towards 100 years is more likely than ever. The implications for businesses, governments and individuals will be monumental. How do we reimagine a longevity-ready society? And how do we engage multiple sectors to source the best ideas from the private sector, government, academia, medicine, philanthropy and beyond? Delving into one central question – how can we create healthful futures? – this session looks at the measures that can be taken now across and between different stakeholders to realize this vision. Taking an intersectional approach, factors considered include public health initiatives, clinical elements, research needs, economic considerations, as well as economic factors and how we might broaden definitions of health.

Multiomics represents a new era of diagnosing patients, understanding diseases, and accelerating precision medicine – merging information from phenomics, genomics, transcriptomics, epigenomics, proteomics, and metabolomics to capture a complete clinical picture. What would it look like if two companies combined their joint passion for this multiomic innovation and a patient-driven purpose? Join Lifera and CENTOGENE to discover how they are catalyzing impact through collaboration.

What are the cost-effective ways to live longer? From nutrient sensing, epigenetic regulation and scientific-based and backed thinking, on why many of us should expect to live to 90 or 95, we consider how we can best use the tools we have to transform our growing field of knowledge into reality.

The complex interaction of our circadian clock with the aging process offers a rich and vital field of research. How do circadian rhythms interplay further with calorie intake fasting, impacting longevity? Discover the latest thinking and research.

What radical new directions can we take, and how do we foster the talent pipeline and existing tools to achieve them? Join leading scientists for a scientific debate forum.

Technology development across the Valley of Death, aka the difficult early phase in technology development, requires a strong transition between original scientific research and commercialisation. How can the often wide gap between research and the end user be bridged? What role do marketing, budgets, risk margins and other factors play? 

Discussions with investors and members of the financial ecosystem as well as philanthropists and foundations. What does today’s funding and financing environment look like? What are the trends around approaches to risk? Who’s entering the market, and where are hopeful biotech companies looking for dollars? Discover the latest on investment targets, impact studies and all areas in and around funding that matter now.

How can we establish a cohesive regulatory framework that promotes innovation whilst ensuring safety and the development of effective healthspan interventions? With health-focused interventions often intersecting between pharmaceuticals, lifestyle modifications and other intersectional factors, we dissect some of the key regulatory issues facing the field of healthy aging. Moving beyond the expectation of compliance and safety we look at the challenges and potential solutions, around the definition of healthspan, longitudinal studies to evaluate intervention impact, clinical trial design with appropriate subjects, endpoints and biomarkers and the development of regulatory frameworks.

In this ‘scientists in discussion’ impact forum, leading scientists delve into epigenetic rejuvenation and the potential to reset and perhaps even resent the aging clock. As well at looking at advances such as cell rejuvenation, we boldly ask just what might the future of this scientific area look like? 

Data plays a pivotal role at the intersection of population health, economics and the evolving landscape of healthy aging. As our understanding deepens, the symphony of data reveals harmonies in the realm of healthy aging, guiding public health initiatives towards a more nuanced approach. By harnessing data, we can tailor interventions to support healthy aging, optimizing healthcare resources and enhancing the quality of life for the elderly. Public health initiatives, guided by robust data analytics, become more precise, addressing the unique needs of aging populations and fostering a society.

This session will introduce the Foundation’s first effort on cultivating emerging investigators in the field of geroscience, emphasizing the importance of nurturing talent to advance our understanding of aging-related processes. The session will introduce the emerging new talent in geroscience and aging research of Saudi Arabia and the international research community and give them the opportunity to share their scientific ideas and progress in the form of short lectures, followed by Q&A on their plans, challenges, opportunities, and the road ahead. 

Basic research into the biology of aging has exploded in the last couple of decades. The enhanced understanding of molecular underpinnings of the process means that now is the right time to bring about efforts to translate these findings into actions that will enhance the human experience of old age. But translation is a complex multidisciplinary and multi-prong effort that requires the participation of scientists, entrepreneurs and regulators, among others. Join senior scientists for a comprehensive exploration of translational research now, covering knowledge-exchange, success stories, challenges – and more! 

Aging is a complex process that involves intricate interconnections at multiple levels from society to molecular systems biology and the advent of omics technologies offers enormous potential for deciphering the processes of aging. Translating our understanding of aging biology into novel therapeutic areas signifies a transformative phase in research – and is rapidly gaining momentum. From identifying new, crucial molecular pathways and networks associated with aging, to pinpoint potential targets for interventions and therapeutics, to predicting and modeling, integrating diverse data sets and supporting the deployment of personalized intervention, systems biology has significant potential to aid the research of aging. What are the latest  insights we are acquiring regarding the genetic, cellular and molecular underpinnings of aging? And equally important, what critical questions remain unanswered at this juncture? 

How can investment unleash outcomes at scale, including around actionable drug development, and to make longevity even bigger than the war on cancer? What do VCs and funders need to make the healthspan sector attractive? Where does philanthropic investment fit in?
This session will have audience Q&A.

From advocacy and awareness and community development to innovation and helping to bridge gaps, the non-profit sector plays a crucial role in society. This special hour will convene stakeholders and parties interested in creating a more effective and sustainable non-profit sector in Saudi Arabia and the region as well as looking at opportunities for transformation in this ecosystem. 

This session will have an audience Q&A.

What does the entrepreneurial domain for healthspan look like now – and how is it evolving? Meet some of the entrepreneurs, investors, hear their stories and join the conversation.

This session will include Q&A.